"We believe a multi-drug strategy is the best approach to battling GBM. There is a significant need for new treatments that can offer GBM patients and their families additional hope," said Stuart A. Grossman, M.D., professor of oncology, medicine and neurological surgery at Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins Hospital and the co-chairperson for this study.
"BSI-201 is a promising agent that has been well tolerated in combination with cytotoxic therapies in patients with solid tumors and potentially addresses a key pathway by which GBM cells resist the effects of existing medications. We are hopeful that BSI-201 will safely potentiate the power of current therapies for GBM and improve survival in this difficult-to-treat cancer," said Jaishri Blakeley, M.D., Assistant Professor of Neurology, Oncology and Neurosurgery at Johns Hopkins and the study chairperson for this study.
"The scientific observations that BSI-201 crosses the blood-brain barrier and has a mechanistic basis to synergize with the standard treatment of GBM makes this a promising study," said BiPar Executive Vice President Barry Sherman, M.D. "It is the promise of this approach that encouraged the leaders of NABTT to evaluate BSI-201 in patients with GBM."
GBM is an aggressive form of brain cancer that strikes 10,000 patients a year in the United States. Currently, patients are often treated with radiotherapy and chemotherapy where the median survival is under 15 months. The initial study phase will evaluate the safety and tolerability of BSI-201 in combination with temozolomide given at standard doses. The Phase 2 component will assess BSI-201 combined with temozolomide plus radiation therapy in
BiPar Sciences Expands Clinical Program for BSI-201, a Novel DNA Repair Inhibitor, in Brain Cancer
Posted by Crush at 4/10/2008 04:13:00 PM
Labels: BiPar Sciences, BSI-201, Multi-drug Strategy, Temodar, TransMolecular Inc.
Buzz Apparel - Support Brain Tumor Research
Fox Valley Brain Tumor Coalition - Journey of Hope Walk
The Journey of Hope is our major fundraiser of the year, allowing us to raise most of the funds that we need to survive. This event is critical to the success of this group, so we hope you can join us!
With over 750 walkers, the Fox Valley Brain Tumor Coalition puts on a great party the Saturday after Labor Day every year. The non-competitive walk is held on the grounds of NeuroSpine Center of Wisconsin. Our paved ½ mile trail is short enough for nearly everyone to make at least one lap around, and is accessible to wheelchairs! For those who like more of a challenge, we encourage as many laps as you are able to do!
The day is a celebration of those fighting brain tumors and remembering those who have lost their battle. The walk starts with a ceremony at the Tree of Hope, with testimonials from those most affected by this disease, as well as a dedication from neurosurgeon Thomas Wascher MD, one of our biggest supporters.
Once you have built up your appetite from the walk, come in to our party tent for a great home-cooked picnic. We have fresh roasted corn-on-the-cob, hamburgers, hot dogs, chips and sweets! Vegetarian selections are available for those with restricted diets.
A huge silent auction, kids games, music, pictures and more makes this party fun for everyone!
As always, dogs are welcome, but should always be on a leash…we will provide water for our four legged friends!
Your registration cost of $10 (yes still only $10 after all these years!!!) includes a great t-shirt with all of our corporate sponsors proudly displayed, lunch and all the fun you can handle!
New this year is our online registration and personal web page, making it easier for your family and friends to support your efforts.
My Team
0 comments:
Post a Comment