4/15/2008 8:49:23 AM Tuesday, before the bell, Sangamo BioSciences, Inc. (SGMO) reported positive data in a mouse tumor model from its ZFP Therapeutic program for the treatment of glioblastoma multiforme, a progressive and fatal brain cancer. Sangamo said it expects to file an Investigative New Drug application for this cell therapy in 2008.
Showing posts with label Research. Show all posts
Showing posts with label Research. Show all posts
Unlocking Mysteries Of Brain Cancer, Stroke
ScienceDaily (2008-04-04) -- New studies will delve into some of the crucial issues surrounding death by brain tumors and stroke. The research will aim to find links between chemical signals in the brain and the reasons why brain tumors or strokes become fatal.
Gene Plays “Jekyll and Hyde” in Brain Cancer
FINDINGS:
Researchers have found that a particular gene is central to the brain cancer glioblastoma and will either fight the tumor or, conversely, help the tumor advance, depending on the tumor’s genetic makeup.
RELEVANCE:
These findings are relevant for the emerging field of personalized medicine. Glioblastoma is a highly aggressive type of cancer for which treatments remain extremely limited. Researchers have long assumed that the gene in question, STAT3, only acts as a tumor inducer, and so have been developing therapeutics that inhibit STAT3. But if STAT3 actually fights tumors in a subset of these cancers, such therapies would do more harm than good. These results may change the way researchers approach not only glioblastoma but other types of cancers as well.
PRINCIPAL INVESTIGATOR:
Azad Bonni, Associate Professor of Pathology, Harvard Medical School
http://www.hmcnet.harvard.edu/pathol/labs/bonni/index.html
Nanotubes Help Advance Brain Tumor Research
ScienceDaily (2008-01-24) -- The potential of carbon nanotubes to diagnose and treat brain tumors is being explored through a new partnership. Nanotechnology may help revolutionize medicine in the future with its promise to play a role in selective cancer therapy.
Drug Study For Brain Cancer Shows Promising Results
ScienceDaily (Dec. 14, 2007) — A clinical study conducted at Henry Ford Hospital on the use of a drug to extend the survival of patients with the most common and aggressive type of brain cancer, has yielded results that were significantly better than expected.
Duke, UNC Researchers Target ‘Achilles Heel’ in Brain Tumors
Editor’s note: This article is part of WRAL Local Tech Wire’s efforts to highlight research at universities across the Carolinas and Georgia.
DURHAM - Researchers at Duke University Medical Center and the University of North Carolina, Chapel Hill are exploiting an "Achilles Heel" of brain tumors that may selectively kill tumor cells while sparing surrounding brain tissue.
DURHAM - Researchers at Duke University Medical Center and the University of North Carolina, Chapel Hill are exploiting an "Achilles Heel" of brain tumors that may selectively kill tumor cells while sparing surrounding brain tissue.
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