Gene Plays “Jekyll and Hyde” in Brain Cancer

FINDINGS:
Researchers have found that a particular gene is central to the brain cancer glioblastoma and will either fight the tumor or, conversely, help the tumor advance, depending on the tumor’s genetic makeup.

RELEVANCE:
These findings are relevant for the emerging field of personalized medicine. Glioblastoma is a highly aggressive type of cancer for which treatments remain extremely limited. Researchers have long assumed that the gene in question, STAT3, only acts as a tumor inducer, and so have been developing therapeutics that inhibit STAT3. But if STAT3 actually fights tumors in a subset of these cancers, such therapies would do more harm than good. These results may change the way researchers approach not only glioblastoma but other types of cancers as well.

PRINCIPAL INVESTIGATOR:
Azad Bonni, Associate Professor of Pathology, Harvard Medical School
http://www.hmcnet.harvard.edu/pathol/labs/bonni/index.html

Posted by Crush at 2/06/2008 04:41:00 PM  

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Buzz Apparel - Support Brain Tumor Research

Fox Valley Brain Tumor Coalition - Journey of Hope Walk

The Journey of Hope is our major fundraiser of the year, allowing us to raise most of the funds that we need to survive. This event is critical to the success of this group, so we hope you can join us!

With over 750 walkers, the Fox Valley Brain Tumor Coalition puts on a great party the Saturday after Labor Day every year. The non-competitive walk is held on the grounds of NeuroSpine Center of Wisconsin. Our paved ½ mile trail is short enough for nearly everyone to make at least one lap around, and is accessible to wheelchairs! For those who like more of a challenge, we encourage as many laps as you are able to do!

The day is a celebration of those fighting brain tumors and remembering those who have lost their battle. The walk starts with a ceremony at the Tree of Hope, with testimonials from those most affected by this disease, as well as a dedication from neurosurgeon Thomas Wascher MD, one of our biggest supporters.

Once you have built up your appetite from the walk, come in to our party tent for a great home-cooked picnic. We have fresh roasted corn-on-the-cob, hamburgers, hot dogs, chips and sweets! Vegetarian selections are available for those with restricted diets.

A huge silent auction, kids games, music, pictures and more makes this party fun for everyone!

As always, dogs are welcome, but should always be on a leash…we will provide water for our four legged friends!

Your registration cost of $10 (yes still only $10 after all these years!!!) includes a great t-shirt with all of our corporate sponsors proudly displayed, lunch and all the fun you can handle!

New this year is our online registration and personal web page, making it easier for your family and friends to support your efforts.

My Team